DiGeorge syndrome is associated with which of the following features?

DiGeorge syndrome is associated with which of the following features?

• A. Hyperparathyroidism
• B. Hypoparathyroidism
• C. Hyperthyroidism
• D. Hypopituitarism

Answer: (B)

DiGeorge syndrome shows up when there’s faulty development of the third and fourth pharyngeal pouches, which normally form the thymus and the parathyroid glands. Because the parathyroids don’t develop properly, parathyroid hormone levels drop, leading to hypoparathyroidism and resulting hypocalcemia. That link—parathyroid underdevelopment causing low PTH and low calcium—is why this feature is the correct association. The other options don’t fit the pattern: excess parathyroid activity isn’t part of DiGeorge, and hyperthyroidism or hypopituitarism aren’t the characteristic problems tied to this syndrome.

DiGeorge syndrome shows up when there’s faulty development of the third and fourth pharyngeal pouches, which normally form the thymus and the parathyroid glands. Because the parathyroids don’t develop properly, parathyroid hormone levels drop, leading to hypoparathyroidism and resulting hypocalcemia. That link—parathyroid underdevelopment causing low PTH and low calcium—is why this feature is the correct association. The other options don’t fit the pattern: excess parathyroid activity isn’t part of DiGeorge, and hyperthyroidism or hypopituitarism aren’t the characteristic problems tied to this syndrome.